This course will explore the process of drug development, from target identification to final drug registration. It will present drug development as a process involving target selection, hit discovery using computer-based methods and combinatorial chemistry/high-throughput screening. Lead identification and optimisation via the use of structure activity series and computational methods will be covered. Safety evaluation, bioavailability, clinical trials, and the essentials of intellectual property, regulatory affairs and commercialisation will also be discussed. Along the way, you will learn about screening assays, computer-aided drug design, and toxicology as applied to the development of new medicines.
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